Popular as a cycling route but also prime for backpacking, the Maah Daah Hey Trail is a 144-mile point-to-point route across the badlands and prairies of western North Dakota. It passes through Theodore Roosevelt National Park and features stark landscapes, abundant wildlife, and unique geological formations.
The Centennial Trail is a 123-mile point-to-point hike in the Black Hills of South Dakota, best hiked from late spring to fall. The trail is mostly well-marked and -graded and can be hiked in 5-10 days.
The Ouachita Trail is a 223-mile point-to-point backpacking route in Oklahoma and Arkansas. It is a blazed trail with frequent shelters, and can be hiked in 10-18 days.